Retired from active duty to train new IMF agents, Ethan Hunt is called back into action to confront sadistic arms dealer, Owen Davian. Hunt must try to protect his girlfriend while working with his new team to complete the mission.
Ethan Hunt has retired from field work for the Impossible Missions Force and instead trains recruits while settling down with his fiancée, Julia Meade, a nurse who is unaware of Ethan’s true job. Ethan is approached by fellow IMF agent John Musgrave about a mission to rescue one of Ethan’s protégés, Lindsey Farris, who was captured while investigating arms dealer Owen Davian. Musgrave has already prepared a team for Ethan: Declan Gormley, Zhen Lei, and his old partner Luther Stickell, who are waiting in Berlin.
The team rescues Lindsey and collects two damaged laptop computers. As they flee via helicopter, Ethan discovers an explosive pellet implanted in Lindsey’s head. Before he can disable it, it goes off and kills her. Back in the U.S., Ethan and Musgrave are reprimanded by IMF Director Theodore Brassel. Ethan learns that Lindsey mailed him a postcard before her capture and discovers a magnetic microdot under the stamp.
IMF technician Benji Dunn recovers enough data from the laptops to determine Davian will be in Vatican City to obtain a mysterious object called the “Rabbit’s Foot”. Ethan plans a mission to capture Davian without seeking official approval. Before leaving, he and Julia have an impromptu wedding at the hospital’s chapel. The team successfully infiltrates Vatican City and captures Davian.
On the flight back to the U.S., Davian threatens to kill Ethan and his loved ones. Ethan then threatens to drop Davian out of the plane, during which Davian overhears Luther calling Ethan by his first name. After landing, Ethan learns that the microdot contains a video of Lindsey warning that she believes Brassel is working with Davian. The convoy taking Davian across the Chesapeake Bay Bridge–Tunnel is suddenly attacked, and Davian escapes. Fearing for Julia’s safety, Ethan races to the hospital, only to find she has already been taken. Davian gives Ethan 48 hours to recover the Rabbit’s Foot in exchange for Julia’s life, but Ethan is soon captured by the IMF.